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Tuesday, August 13, 2013
Aldosterone some information
Aldosterone the nature and Stability:
1 Stability stable
2 Materials to avoid acid chlorides, acid anhydrides, strong oxidizing agents
3 Conditions to avoid heat
4 Hazardous Polymerization Will not polymerize.
5 decomposition products hydrogen bromide
Aldosterone storage methods:
Storage Precautions Store in a cool, ventilated warehouse. Keep away from fire and heat. Keep container tightly closed. Should oxidants, food chemicals stored separately and avoid mixing reservoir. Explosion-proof lighting, ventilation facilities. Prohibit the use of easy to produce sparks of mechanical equipment and tools. Storage areas should be equipped with spill response equipment and materials suitable host.
Aldosterone synthesis method:
By the o-aminophenol by diazotization, bromination derived: (a) diazotized o-aminophenol with water, stir, add concentrated sulfuric acid and ice cooling to below 5 ℃. Slowly sodium nitrite solution, the reaction temperature was maintained below 5 ℃ diazonium salts. (2) adding cuprous bromide bromide hydrobromide was dissolved with stirring heavier diazonium salt, the addition was complete stirring 0.5h, placement, steam distillation to a distillate oil tilting up, standing separation of the oil, the oil vacuum distillation derived.
Aldosterone uses:
1. The manufacture of disinfectants used in organic synthesis, drug intermediates, solvents.
2 used in organic synthesis.
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