1, pharmacological Cephalexin belongs to the first generation of cephalosporin, antibacterial spectrum and similar cefalotin, but its antimicrobial activity is worse than the latter. In addition to enterococcus, methicillin resistant staphylococcus aureus, streptococcus pneumoniae, hemolytic streptococcus, produce or not produce penicillin enzyme most of staphylococcus aureus strains is sensitive to the goods. The goods has good antibacterial effect to neisseria bacteria genera, but poor haemophilus influenzae on the sensitivity of the goods; The goods on the part of the e. coli, singular deformation coli, salmonella and shigella has certain antibacterial activity. The rest of the enterobacteriaceae bacteria, acinetobacter, pseudomonas aeruginosa and bacteroides fragilis present resistance to the goods. Fusiformis and WeiRong coccus is sensitive to the goods, usually anaerobic gram-positive coccus is sensitive to the goods to moderate.
2, toxicology Cephalexin mice oral median lethal dose of 2.6 g/kg.
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