Immunogen
Synthetic sulfated CCK8 conjugated to KLH.
General description
Cholecystokinin (CCK) belongs to gastrointestinal hormone ancestors is a neuropeptide hormone and neurotransmitter usually present in gastrointestinal (GI) amplitude and the axial afraid arrangement (CNS). CCK functions cover agitator beard from pancreas, acrimony float contraction, abdominal motility; CCK will aswell arrest gastrin induced acerbic secretion2,3. Anti-cholecystokinin (26-33) (CCK8) antibiotic can be acclimated in radioimmunoassay to actuate claret CCK4. This artefact is aswell advantageous for the abstraction of approach of action, cogwheel tissue announcement and intracellular and subcellular localization of CCK in CNS and in neuroendocrine beef of digestive system. Anti-CCK8 reacts accurately with sulfated CCK8 and shows cantankerous acuteness with unsulfated CCK8 and caerulein.
Application
Anti-cholecystokinin (26-33) (CCK8) antibiotic can be acclimated to ascertain CCK peptide in pancreatic blight beef by immunocytochemistry1. It may aswell be acclimated for dot blemish immunoassay.
from:
Elisa assay kits
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