Properties of Flunarizine dihydrochloride

CAS No.    30484-77-6
Chemical Name:    Flunarizine dihydrochloride
Synonyms:    r14950;Issium;Mondus;kw-3149;Flunarl;Flugeral;Gradient;Dinaplex;Flunagen;Fluxarten
CBNumber:    CB2377940
Molecular Formula:    C26H28Cl2F2N2
Formula Weight:    477.42
Chemical Properties
White Solid
Usage
antipsychotic, H1 antihistamine
Usage
Calcium channel blocker; fluorinated derivative of Cinnarizine. Vasodilator (cerebral and peripheral). This is the labeled analog.
Biological Activity
Dual Na + /Ca 2+ channel blocker; a cerebral and peripheral vasodilator. Neuroprotective.
Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.
storage temp:  2-8°C.
from:Natural standard substance