What is the Fenbufen

Fenbufen is white or kind of white pieces. This product is white or white crystalline powder; Odourless; Taste sour. This product dissolved in ethanol, almost insoluble in water; Easily dissolved in a hot alkaline solution.

Fenbufen is a relatively new type of long-term non-steroidal anti-inflammatory and analgesic drug. According to animal studies, although the anti-inflammatory and analgesic action of this crystal was lower than those of indomethacin, but stronger than aspirin. Toxicity is smaller than indomethacin, gastrointestinal side effects than aspirin and other non-steroidal anti-inflammatory and analgesic drug. The pharmacological research showed that the crystal in the body metabolism into PCB ethyl ester, which inhibits the synthesis of prostaglandins, thereby blocking the role of inflammatory mediators, think this is this article main mechanism of anti-inflammatory effects. Finn cloth as a precursor of biphenyl ethyl ester, can avoid taking active metabolites directly after oral stimulation of the gastrointestinal tract. The domestic trial in rheumatoid arthritis, rheumatoid arthritis, the total effective rate was 87%. This drug is generally can make the chain of rheumatoid factor, blood sedimentation, turn back to normal or "O" and other indicators. Pathological examination did not see the main viscera have obvious pathological changes. Two hours after the oral blood concentrations of peak value. T 1/2 for 12 ~ 17 hours. Used for rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gout treatment, etc. Also used for toothache, pain pain after surgery, trauma, pain, etc.