Sunday, December 29, 2013

A brief introduction CD4 ELISA Kit



CD4 cells are a kind of important immune cells in the body's immune system, CD4 expression mainly in T helper (Th) cells, is Th cell TCR identify antigen for the receptor, the peptide section with MHC class Ⅱ molecules combined with, participate in Th cell antigen which is the identification of signal transduction, CD4 receptors and HIV, the AIDS virus attacks object is CD4 cells, so the test result on the immune function of patients with AIDS treatment effect of judgment, and to the important role in the judgment.
Normal adult CD4 cells per cubic millimeter in 500 to 1600, HIV infection of CD4 cells developed progressive or irregularity decline, marked the immune system is severely damaged, when CD4 cells per cubic millimeter less than 200 a, may be a variety of opportunistic infection or tumor.
Principle of HIV/AIDS infection: white blood cells are killing foreign microbe guardians of the human body, it mainly contains the CD4 and CD8 and CD4 cells play the role of "informant", CD8 cells is engulf bacteria, when AIDS virus enters the body, it will be abducted CD4 cells, CD8 cells become "the blind and the deaf", HIV invades white blood cells, then the white blood cells as their own breeding hotbed.

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