A multitude of antiepileptic drugs in current valproic acid is a wide clinical application, high curative effect and safety of good choice, broad spectrum drugs. Valproic acid (DE ba jin? Not only can be used to treat various kinds of epilepsy of generalized seizures, especially the absence seizure and stiffness - clonus attack, can also be used for partial onset seizures.
Side effects: compared with carbamazepine and valproic acid has obvious tremor and weight gain effects, but less rash. The acute side effects of valproic acid, mainly (see more oral dosage forms) reaction of gastrointestinal tract and tremors. Tremor is a mild excessive performance, reduce the dose can be controlled.
Valproic acid varied chronic toxicity reaction performance. The most common is weight gain, high blood ammonia is common, but for most patients with no clinical significance. Treatment dose valproic acid will not affect cognitive function, unless you use high doses.
Atopic side effects are rare, but the risk is bigger. Thrombocytopenia associated with dose, and the severity of the surgical research shows that thrombocytopenia has nothing to do with bleeding; The incidence of pancreatitis is about 1/40 of 000; The incidence of hepatitis is about 1/10 1/40 000 ~ 000. In recent years, with the overall understanding of the risk factors, as well as the strict monitoring measures taken, did not have any reports of deaths due to pancreatitis or hepatitis.
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