What is captopril

What is captopril? For many people, captopril may have never heard of it, and here's the introduction

Captopril is an ACE inhibitor (ACE or ACEI) that is used to treat high blood pressure and certain types of congestive heart failure. As the first of the ACEI drugs, captopril was considered a breakthrough in drug treatment due to its new mechanism and revolutionary development process.

An artificial synthesis of non-peptide angiotensin converting enzyme (ACEI) inhibitors, mainly in the renin-angiotensin-aldosterone system (RAAS) system. Angiotensin converting enzyme inhibition of RAAS system (ACEI), blocking angiotensin Ⅰ conversion or angiotensin Ⅱ, and inhibit the aldosterone secretion, reduce water sodium retention. There is a clear reduction of hypertension in many types of hypertension, and can improve the heart function of patients with congestive heart failure. The reduction of blood pressure in patients with different renin type of hypertension with high renin and normal renin; It was also evident that the lower renal type was reduced after the addition of diuretics. Its antihypertensive mechanism for the inhibition of angiotensin converting enzyme activity and lower levels of angiotensin Ⅱ, diastolic small artery, etc. This product has low to moderate pressure effect, can reduce the peripheral vascular resistance, increase the blood flow of the kidney, not the reflectional heart rate quickens. This article can reduce blood pressure by the following mechanism: inhibit angiotensin converting enzyme, and make angiotensin I to reduce AngII, resulting in vasodilation. It also reduces the secretion of aldosterone, which is good for sodium. Specific renal vessel dilation is also a function of sodium; By suppressing the hydrolysis of the delayed peptides and reducing the inactivation of the delayed peptides; In addition, it inhibits the formation of local angiotensin I in the vascular tissue and the heart muscle. Can improve the heart function of heart failure patient.