What's the role of Temozolomide

What's the role of Temozolomide? Many people don't know much about it, and here's the introduction:

The primary agent for tamoxazolamine is white or light brown/pale pink powder, and the relative molecular mass is 194.15. PH7 easy decomposition, from methylene chloride crystallization, melting point 212 ℃ (decomposition). UV maximum absorption (95% ethanol) : 327nm. It is slightly soluble in dimethylsulfone, which is dissolved in water, dissolves in methanol and is almost insoluble in ethanol, and is dissolved in acetic acid. Clinical use of the active metabolite MTIC, which can be spontaneously and rapidly decomposed in the body, produces an anti-tumor effect.

For antitumor medicine. Spontaneous and degrade more quickly in the body can produce active metabolite MTIC, and anti-tumor effect. This product is alkylating agent imidazoles, antitumor drugs in nitrogen is miaow thiazole amine analogues, it is one of the most effective drug in the clinical treatment of brain tumors. Studies have shown that has obvious curative effect to all kinds of animal tumors, including TLX5 lymphoma, oral this product by subcutaneous transplantation in no thymic mice brain tumor has obvious curative effect. It can pass the blood brain barrier, clinical treatment of brain or intrathecal tumor and advanced melanoma brain metastases, and adult pleomorphic glioblastoma keloma. Its side effects, small tolerance.