The ornithine decarboxylation acknowledgment catalyzed by ornithine decarboxylase is the aboriginal and committed footfall in the amalgam of polyamines, decidedly putrescine, spermidine and spermine. Polyamines are important for stabilizing DNA structure, the DNA bifold strand-break adjustment alleyway and as antioxidants. Therefore ornithine decarboxylase is an capital agitator for corpuscle growth, bearing the polyamines all-important to balance anew actinic DNA. Lack of ODC causes corpuscle apoptosis in beginning mice, induced by DNA damage.
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