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Friday, November 22, 2013
The first Androstenone in mammals
Androstenone (5α-androst-16-en-3-one) is a steroid begin in both macho and changeable diaphoresis and urine. It is aswell begin in boar's saliva, and in celery cytoplasm. Androstenone was the aboriginal beastly pheromone to be identified. It is begin in top concentrations in the saliva of macho pigs, and, if sniffed by a changeable pig that is in heat, after-effects in the changeable bold the alliance stance. Androstenone is the alive additive in 'Boarmate', a bartering artefact fabricated by DuPont awash to pig farmers to analysis sows for timing of bogus insemination.
There are two altered genotypes that acquiesce an alone to that appears to that appears to smell androstenone. The aboriginal genotype, which consists of two absolutely anatomic copies of the gene, is the RT/RT allele, and the additional is the RT/WM allele. The OR7D4 receptor has two non-synonymous individual nucleotide polymorphisms, which could could cause the gene to accept two amino acerbic substitutions, which in about-face could could cause the receptor to act differently. Those in control of the two able genes, (RT/RT) for OR7D4 tend to call the odor for the steroid as the odor of dried urine. Those with alone one gene (RT/WM) about declared the odor as anemic or were not able to ascertain it. They can aswell acquisition the that appears to that appears to smell 'pleasant', 'sweet' or 'similar to vanilla'.
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