Sunday, August 25, 2013

Hydnocarpic acid-related information


Flacourtiaceae woody plants, leaf, leaves alternate, rarely opposite or whorled (China no); stipules small. Flowers small, actinomorphic, unisexual or bisexual, usually dioecious or hybrid strains; inflorescence racemose corymbs, panicles, clusters of inflorescence, etc., usually 2 to 7 calyx, petals deposit or absent; Tori usually with glands, stamens usually numerous, scarce number of anthers 2-celled, ovary superior, upper half, rarely inferior, 1 to 2 rooms, parietal placentation, ovules anatropous. The fruit is a capsule, berry, drupe (China without). Seed aril, a few winged, endosperm, cotyledon large. Slightly fragrant flowers, the nectary, is insect-pollinated plants, pregnancy rate, the results are more. Pollen roughly nearly spherical, nearly prolate to prolate. Size (12 ~ 36.6) × (8 ~ 40) microns. With 2 to 3 or 3 colporate intended colporate, bore horizontal length, contour explicitly or implicitly, how thick the outer to the inner wall. Finely reticulate surface. Chromosome number x = 10,11,12.
Economic Value:
Flacourtiaceae versatile plants, medicinal plants Hydnocarpus genus, genus horse egg fruit, oak genus, etc., several Hydnocarpus and horse egg fruit Hydnocarpus oleic acid (Chaulmoogric acid, C18H32O2) and sub-oleic Hydnocarpus (Hydnocarpic acid, C16H28O2) for the treatment of leprosy; Hill peel the genus Jatropha oil yield 32.82%, 28.43% oil content seeds, edible oils and treated for light industrial use; Sri Lanka day feeding wood (female students) is tall trees, fine-grained, solid material for a variety of timber, is also a fine tropical tree species; snuffbox trees, large spiny wooden fruit edible fruit; Philippine oak, white background red wood sub endangered; horse egg fruit, Hainan Hydnocarpus hairless day material wood as national key protected plants, white-backed red sub-wood, pearl thorn Hiiragi, Hainan day feeding wood, Guangxi day feeding wood, Quang Nam-day feeding wood, were pulse-day feeding wood, short calyx day feeding wood, wide petal day feeding wood, wood materials Brachystachyum day, willow day feeding wood, mountain Calligonum, goats hornbeam, Yunnan, Guizhou, goat horn tree, flower thinning oak, such as China, Yunnan blackmailed crisp endemic.

More about:Hydnocarpic acid manufacturer
From:Natural herbal extracts

Tuesday, August 20, 2013

Sulphadimidine related presentations





Sulfa drugs for the broad spectrum antibacterial agents, similar in structure to para-aminobenzoic acid (PABA), PABA competitive action with the bacterial two-synthase in vivo, thereby preventing bacteria PABA synthesis required for the process of folic acid, reduced folate metabolic activity with the amount, while the latter is a bacterial purine synthesis, thymidine, and DNA (DNA) of the necessary material, thus inhibiting bacterial growth and reproduction. Sulfa drugs action can be PABA and its derivatives (procaine, tetracaine) antagonized, in addition pus and the organization of the existence of decomposition products from the antagonism, because it provides the necessary material for bacterial growth.
Sulphadimidine is an antibacterial sulfa drugs; induction of CYP3A4 expression, and by N-acetyl transferase acetylation; exhibit pharmacokinetics of dependence, by means of the male specific isoforms metabolize CYP2C11; inhibit dihydrofolate synthesis enzymes, to hinder the effect of folate synthesis. With sulfadiazine equivalent effect. For the treatment of hemolytic streptococcus, meningococcus, pneumococcus infections, lasting.
As a feed additive for the prevention of hemolytic streptococcus and staphylococcus infections, where the main treatment of fowl cholera, fowl typhoid, coccidiosis and so on.
For the control of Staphylococcus and Streptococcus infections solubility of hemolytic streptococcus and other bacteria are inhibited pleurisy bacteria, the main treatment of fowl cholera, fowl typhoid, coccidiosis, etc.
As antibacterial agents for the prevention of hemolytic streptococcus and staphylococcus infections, for the treatment of hemolytic streptococcus, meningococcus, pneumococcus infections. Primarily for the treatment of fowl cholera, fowl typhoid, coccidiosis and so on.


More about:Sulphadimidine Sales
From:Acridine Raw Material

Tuesday, August 13, 2013

Aldosterone some information




Aldosterone the nature and Stability:
1 Stability stable
2 Materials to avoid acid chlorides, acid anhydrides, strong oxidizing agents
3 Conditions to avoid heat
4 Hazardous Polymerization Will not polymerize.
5 decomposition products hydrogen bromide

Aldosterone storage methods:
Storage Precautions Store in a cool, ventilated warehouse. Keep away from fire and heat. Keep container tightly closed. Should oxidants, food chemicals stored separately and avoid mixing reservoir. Explosion-proof lighting, ventilation facilities. Prohibit the use of easy to produce sparks of mechanical equipment and tools. Storage areas should be equipped with spill response equipment and materials suitable host.

Aldosterone synthesis method:
By the o-aminophenol by diazotization, bromination derived: (a) diazotized o-aminophenol with water, stir, add concentrated sulfuric acid and ice cooling to below 5 ℃. Slowly sodium nitrite solution, the reaction temperature was maintained below 5 ℃ diazonium salts. (2) adding cuprous bromide bromide hydrobromide was dissolved with stirring heavier diazonium salt, the addition was complete stirring 0.5h, placement, steam distillation to a distillate oil tilting up, standing separation of the oil, the oil vacuum distillation derived.

Aldosterone uses:
1. The manufacture of disinfectants used in organic synthesis, drug intermediates, solvents.
2  used in organic synthesis.




More about:Aldosterone sales
From:Hormonehome

Monday, August 12, 2013

Testosterone propionate introduce the function, etc.




Function of the role: Testosterone propionate role with testosterone, methyltestosterone same, but the duration of action than intramuscular lasting injections every 2 to 3 days once. Clinically applicable testis syndrome, cryptorchidism, male hypogonadism; gynecological diseases menorrhalgia, uterine fibroids; senile osteoporosis and aplastic anemia. By stimulating the kidneys secrete erythropoietin role or have a direct stimulating effect on the bone marrow. Primary testicular hypofunction androgen replacement therapy; genital dysplasia.
Large doses can cause virilization, edema, liver damage, jaundice, and dizziness. Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer patients and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Delayed puberty and dwarfism; variety of chronic wasting disease.

Characterized as: the goods in the body first converted to 5α dihydrotestosterone (5α-dihyrotesterone), later with cell receptors, into the nucleus, chromatin function, activation of RNA polymerase, promote protein synthesis and cell metabolism. In addition, testosterone propionate by erythropoietin stimulate red blood cell formation and differentiation. Although this product can be absorbed orally, but will quickly destroy the liver and failure, it is generally used intramuscular injection. After intramuscular injection of testosterone propionate, slow absorption, and its delay onset time 2-4 days. In the blood, 98% of testosterone and sex hormone binding globulin, only 2% of free form. Half-life of 10-20 minutes. Testosterone inactivated in the liver, metabolites androsterone and DHEA original bile alkyl ketones. 90% of them with glucuronic acid and sulfuric acid combined form from the urine. Approximately 6% of the product is non-binding form by the bile, which can still be a small part of resorption, formation of enterohepatic circulation.

Adverse reactions :17-α alkyl substituted testosterone has some toxicity to the liver and can cause jaundice. Long been used in female patients may cause acne, hirsutism, deepening voice, changes in libido and other masculine performance. When they find liver dysfunction and female masculine performance, should be discontinued immediately. Large doses can cause virilization, edema, liver damage, jaundice, and dizziness.
Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Pregnant and lactating women, prostate cancer patients with disabling; medication should regularly check liver function, liver damage if you should reduce the dosage or disabled; prepubescent children should be applied in reduction, and every 6 months bone age measured 1 .


More about:Testosterone propionate sales
From:Hormonehome

Wednesday, August 7, 2013

Nandrolone decanoate (Deca-Durabolin) Some notes





Nandrolone decanoate (Deca-Durabolin) is white or milky white or light yellow crystal at the end, no foul. Mainly used for protein deficiency, such as chronic wasting disease, premature children, malnutrition, weight loss after surgery frail, loss of appetite, chronic diarrhea, but also for difficult to heal fractures, osteoporosis.
Note:
1, liver, kidney, heart dysfunction careful.
2. Prostatic hyperplasia, prostate cancer, high cholesterol, hypertension patients and pregnant women, disabled.
3. At below 10 ℃ shading confined preservation.
Other Considerations with Nandrolone.
4. Long-term heavy use of the product can cause sodium retention, liver damage, slightly masculine women and so on.


More about:Nandrolone decanoate(Deca-Durabolin) sales
From:Hormonehome

Monday, August 5, 2013

Ethinyl Estradiol indications



Ethinyl estradiol is 3 - hydroxy-19 - demethyl-17α-pregna-1, 3,5 (10) - triene-20 - alkynyl -17 - ol. Calculated on dry goods, including C20H24O2 should be 97.0% ~ 103.0%. White or almost white crystalline powder; odorless. This product is ethanol, propanol or ether soluble, dissolved in chloroform, insoluble in water. The product of the melting point (Appendix Ⅵ C) to 180 ~ 186 ℃.
Indications:
⒈ estrogen deficiency, treatment of female gonadal dysfunction, amenorrhea, menopausal syndrome, etc.; for advanced breast cancer (postmenopausal women), the treatment of advanced prostate cancer; drugs in combination with progesterone, can inhibit ovulation, can be used for contraceptives. The main clinical medicine as inhibiting ovulation; also used in pediatric cryptorchidism and androgen excess, pituitary tumors. For the diagnosis of hypothalamic - pituitary - gonadal dysfunction, according to which changes in gonadotropin and sex hormone levels.
⒉ treatment due to inadequate secretion of gonadotropin hypogonadism amenorrhea and infertility, infertility multiple ovarian follicles. Amenorrhea associated with weight loss, should be corrected with diet weight. Also used for prostate cancer (often with cyproterone or fluorine carboximide combined), delayed puberty or early and endometrial bit different. Mainly used in suppressing ovulation to achieve the purpose of contraception.



More about:Ethinyl Estradiol sales
From:Hormonehome

Thursday, August 1, 2013

Gestodene use and interaction



Gestodene purposes: as anti-progesterone drug
Pharmacology and Applications: To date, the strongest effect of progesterone and a minimum dose contraceptives. Its progestin norethindrone activity of L-A 2 times, no androgen and estrogen activity, there are anti-estrogen effect. Rapidly and completely absorbed orally, after 1 to 2 hours peak blood concentration, bioavailability 100 percent, eliminating t1/28 hours. Composite sheet consisting of clinical and ethinyl estradiol or three photos as short-acting oral contraceptives. Due to its contraceptive effect is reliable, cycle control, and on the favorable impact on lipid metabolism can improve hdl, so for the most ideal kind of oral contraceptives.

Interactions:
1, can be elevated plasma concentration of the drug Gestodene: eg atorvastatin, vitamin C and other drug metabolizing enzyme preparations such as fluconazole. Triacetyl oleandomycin used simultaneously with combined oral contraceptives may increase the incidence of intrahepatic cholestasis of risk.
2, can Gestodene contraceptive effect lowering drugs; antimicrobial agents, especially broad-spectrum antibiotics, drug metabolizing enzyme inducers such as rifampicin, phenobarbital, phenytoin, etc., should be avoided while taking.
3, Gestodene affect the efficacy of other drugs, it has weakened the role of anti-hypertensive drugs, anticoagulants and hypoglycemic agents; make enhanced efficacy of tricyclic antidepressants.
4, if used simultaneously with other drugs may occur drug interactions, please consult your physician or pharmacist.



More about:Gestodene sales
From:Hormonehome