Gestodene purposes: as anti-progesterone drug
Pharmacology and Applications: To date, the strongest effect of progesterone and a minimum dose contraceptives. Its progestin norethindrone activity of L-A 2 times, no androgen and estrogen activity, there are anti-estrogen effect. Rapidly and completely absorbed orally, after 1 to 2 hours peak blood concentration, bioavailability 100 percent, eliminating t1/28 hours. Composite sheet consisting of clinical and ethinyl estradiol or three photos as short-acting oral contraceptives. Due to its contraceptive effect is reliable, cycle control, and on the favorable impact on lipid metabolism can improve hdl, so for the most ideal kind of oral contraceptives.
Interactions:
1, can be elevated plasma concentration of the drug Gestodene: eg atorvastatin, vitamin C and other drug metabolizing enzyme preparations such as fluconazole. Triacetyl oleandomycin used simultaneously with combined oral contraceptives may increase the incidence of intrahepatic cholestasis of risk.
2, can Gestodene contraceptive effect lowering drugs; antimicrobial agents, especially broad-spectrum antibiotics, drug metabolizing enzyme inducers such as rifampicin, phenobarbital, phenytoin, etc., should be avoided while taking.
3, Gestodene affect the efficacy of other drugs, it has weakened the role of anti-hypertensive drugs, anticoagulants and hypoglycemic agents; make enhanced efficacy of tricyclic antidepressants.
4, if used simultaneously with other drugs may occur drug interactions, please consult your physician or pharmacist.
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From:Hormonehome
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